Oxidation: The Most Common Pathway for the Pro-drugs Bio Precursors Activation

Oxidation of inactive prodrug (that their mode action is not via linkage carrier, but occur through modification molecules which are called the bio precursor) to active parent drug design generally methods strategies that aim improve physicochemical and pharmacological properties drugs such as increases bioavailability, water solubility and/or duration action.The goal this review study up-to-date advances in prodrug’s oxidative activation N- O- dealkylation, deamination, N-oxidative S-oxidative important produce parents’ drugs. reactions great importance most cancerous diseases begin with these reactions.